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Lysine-rich diet
Liver disease
Long-term use in pregnant women
Pregnancy, breastfeeding
Risk of death in certain patients
Serious side effects
Some deaths have been reported with long-term use of bupropion products. In these cases, there is evidence or reasonable indication of an association with liver damage [see Warnings and Precautions (5.2) Clinical Pharmacology (12.3)].
Seizures
The use of bupropion may cause seizures. It is strongly recommended that bupropion not be
Buy metformin canada used during a seizure, generic pharmacy branches including seizures due to epilepsy [see Warnings and Precautions (5.2) Clinical Pharmacology (12.3)].
Drug Interactions
Drugs that inhibit neurotransmitter reuptake such as MAO inhibitors, antihistamines, and serotonin-norepinephrine reuptake inhibitors [see Drug Interactions (7.1) and Clinical Pharmacology (12.3)].
Alcohol
The clinical studies of bupropion for depression have not shown impairment of the ability to drive or use machinery operate dangerous machines or activities, although some patients have been able to perform tasks that would normally be associated with driving. Bupropion doses of less than 100 mg/day should not be used by patients who have been drinking alcohol. [See Warnings and Precautions (5.3) Clinical Pharmacology (12.3)].
Bupropion may cause elevated blood alcohol levels. levels have been reported in the clinical trials Wellbutrin 300mg $51.52 - $2.58 Per pill for this drug. Bupropion doses of less than 100 mg/day should not be used by alcohol-intoxicated patients.
A substantial portion of patients treated with bupropion experienced an increase in the mean volume of distended veins, or asymptomatic arterial hypertension. If these symptoms persist, contact your healthcare provider.
Some individuals who have experienced such symptoms significant reductions in cardiovascular activities to the point that they may be unable to safely perform their work tasks. There is insufficient evidence from controlled clinical trials to determine if any patients will experience adverse events as a result of such reduction in cardiovascular activities those patients [see Drug Interactions (7.1) and Clinical Pharmacology (12.3)].
Carcinogenesis, Mutagenesis, Impairment of Fertility
No evidence has been found in humans or the experimental animals conducted in animal testing that bupropion has caused cancer or that it can cause mutagens.
Bupropion does not appear to be mutagenic in vitro.
Bupropion had no adverse effects on fertility in animal reproduction studies.
Bupropion and Fertility
It is not known whether bupropion causes loss of bone mineral density.
Interactions with Other Drugs and.
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